PMS 12 · Membrane trafficking, adhesion and signal transduction
Friday .::. 28 September .::. 14:00-16:00
PMS.12 · 0+P1 
Nervous system alterations in Drosophila melanogaster sphingolipid metabolic pathway mutants
M.A. Zordan1, A. Magnabosco1, G. Harris3, A. Megighian2
1Dept of Biology, Univ. Padova (Padova); 2Dept of Human Anatomy and Physiology, Univ. of Padova (Padua); 3Dept Of Cell & Mol. Biol., San Diego State Univ. (San Diego, CA, USA)

Nervous system alterations in Drosophila melanogaster sphingolipid metabolic pathway mutants
M.A. Zordan1, A. Magnabosco1, G. Harris3, A. Megighian2
1Dept of Biology, Univ. Padova (Padova); 2Dept of Human Anatomy and Physiology, Univ. of Padova (Padua); 3Dept Of Cell & Mol. Biol., San Diego State Univ. (San Diego, CA, USA)
PMS.12 · 0+P4 
T3 action on pancreatic β cell function: a possible role for TRβ1 in the Akt pathway
C. Verga Falzacappa1,2, V. Patriarca1,2, B. Bucci2, S. Michienzi1,2, C. Mangialardo1,2, G. Moriggi1,2, A. Stigliano1,2, S. Misiti1,2
1Chair of Endocrinology, II Faculty of Medicine, Univ. La Sapienza (Rome); 2Centro Ricerca AFaR, Ospedale San Pietro FBF (Rome)

T3 action on pancreatic β cell function: a possible role for TRβ1 in the Akt pathway
C. Verga Falzacappa1,2, V. Patriarca1,2, B. Bucci2, S. Michienzi1,2, C. Mangialardo1,2, G. Moriggi1,2, A. Stigliano1,2, S. Misiti1,2
1Chair of Endocrinology, II Faculty of Medicine, Univ. La Sapienza (Rome); 2Centro Ricerca AFaR, Ospedale San Pietro FBF (Rome)
PMS.12 · 0+P6 
A novel function for the Rab5 effector Rabenosyn-5 in planar cell polarity
G. Mottola1,2, A.K. Classen2, M. González-Gaitán3, S. Eaton2, M. Zerial2
1Dept Medical Biochemistry and Biotechnology, Univ. Naples "Federico II" (Naples); 2Max Planck Institute of Molecular Cell Biology and Genetics (Dresden, Germany); 3Dept Biochemistry and Dept Molecular Biology, Univ. Geneva (Geneva, Switzerland)

A novel function for the Rab5 effector Rabenosyn-5 in planar cell polarity
G. Mottola1,2, A.K. Classen2, M. González-Gaitán3, S. Eaton2, M. Zerial2
1Dept Medical Biochemistry and Biotechnology, Univ. Naples "Federico II" (Naples); 2Max Planck Institute of Molecular Cell Biology and Genetics (Dresden, Germany); 3Dept Biochemistry and Dept Molecular Biology, Univ. Geneva (Geneva, Switzerland)
PMS.12 · 0+P7 
RILP is involved in the biogenesis of multivesicular bodies
C. Progida1, L. Malerød2, S. Stuffers2, A. Brech2, G. Ventimiglia1, H. Stenmark2, C. Bucci1
1Dept Scienze e Tecnologie Biologiche ed Ambientali, Univ. del Salento (Lecce); 2Dept of Biochemistry, Norwegian Radium Hospital and Centre for Cancer Biomedicine, Univ. of Oslo, Montebello (Oslo, Norway)

RILP is involved in the biogenesis of multivesicular bodies
C. Progida1, L. Malerød2, S. Stuffers2, A. Brech2, G. Ventimiglia1, H. Stenmark2, C. Bucci1
1Dept Scienze e Tecnologie Biologiche ed Ambientali, Univ. del Salento (Lecce); 2Dept of Biochemistry, Norwegian Radium Hospital and Centre for Cancer Biomedicine, Univ. of Oslo, Montebello (Oslo, Norway)
PMS.12 · P13 
Alfa-Diacylglicerol kinase mediates HGF-dependent effect in Kaposi’s sarcoma cells
A. Zamperone1, D. Locarno1, A. Cerutti1, G. Baldanzi2, F. Chianale2, E. Rainero2, A. Graziani2, M. Prat1
1Laboratory of Histology, Dept Medical Sciences, Univ. del Piemonte Orientale "A. Avogadro" (Novara); 2Laboratory of Biochemistry, Dept of Medical Sciences, Univ. del Piemonte Orientale "A. Avogadro" (Novara)

Alfa-Diacylglicerol kinase mediates HGF-dependent effect in Kaposi’s sarcoma cells
A. Zamperone1, D. Locarno1, A. Cerutti1, G. Baldanzi2, F. Chianale2, E. Rainero2, A. Graziani2, M. Prat1
1Laboratory of Histology, Dept Medical Sciences, Univ. del Piemonte Orientale "A. Avogadro" (Novara); 2Laboratory of Biochemistry, Dept of Medical Sciences, Univ. del Piemonte Orientale "A. Avogadro" (Novara)
PMS.12 · P16 
Structural and functional differences of Krit1A and Krit1B isoforms: a framework for understanding CCM pathogenesis
F. Francalanci1, M. Avolio1, L. Goitre1, P. Guazzi2, E. Ferro2, G. Tarone1, L. Trabalzini1, S.F. Retta1
1Molecular Biotechnology Center, Dept of Genetics, Biology and Biochemistry, Univ. Turin (Turin); 2Dept of Molecular Biology, Univ. of Siena (Siena)

Structural and functional differences of Krit1A and Krit1B isoforms: a framework for understanding CCM pathogenesis
F. Francalanci1, M. Avolio1, L. Goitre1, P. Guazzi2, E. Ferro2, G. Tarone1, L. Trabalzini1, S.F. Retta1
1Molecular Biotechnology Center, Dept of Genetics, Biology and Biochemistry, Univ. Turin (Turin); 2Dept of Molecular Biology, Univ. of Siena (Siena)
PMS.12 · P17 
PKCβII docks on RACK1 in mammalian ribosomes and modulates initiation of translation
S. Grosso1,2, V. Volta1,2, L. Sala1, L. Magri1, M. Vietri1,2, D. Ron4, P.C. Marchisio3, S. Biffo1,2
1Molecular Histology and Cell Growth, DIBIT-HSR (Milan); 2DISAV, Univ. of Eastern Piedmont (Alessandria); 3Univ. Vita Salute San Raffaele (Milan); 4Dept of Neurology, Ernest Gallo Research Center (San Francisco, California, USA)

PKCβII docks on RACK1 in mammalian ribosomes and modulates initiation of translation
S. Grosso1,2, V. Volta1,2, L. Sala1, L. Magri1, M. Vietri1,2, D. Ron4, P.C. Marchisio3, S. Biffo1,2
1Molecular Histology and Cell Growth, DIBIT-HSR (Milan); 2DISAV, Univ. of Eastern Piedmont (Alessandria); 3Univ. Vita Salute San Raffaele (Milan); 4Dept of Neurology, Ernest Gallo Research Center (San Francisco, California, USA)
PMS.12 · P20 
Expression and functional role of TRPC channels in developing neurosecretory cells
S. Antoniotti1,2,3, P. Ariano1,2,3, S. Dalmazzo1,2,3, A. Gilardino1,2,3, D. Lovisolo1,2,3
1Dept Animal and Human Biology, Univ. Turin (Turin); 2NIS Centre of Excellence, Univ.Turin (Turin); 3CNISM Interuniversitary National Consortium for the Science of the Matter (Turin)

Expression and functional role of TRPC channels in developing neurosecretory cells
S. Antoniotti1,2,3, P. Ariano1,2,3, S. Dalmazzo1,2,3, A. Gilardino1,2,3, D. Lovisolo1,2,3
1Dept Animal and Human Biology, Univ. Turin (Turin); 2NIS Centre of Excellence, Univ.Turin (Turin); 3CNISM Interuniversitary National Consortium for the Science of the Matter (Turin)
PMS.12 · P25 
β-Arrestins as signaling intermediates in chemokine-induced leukocyte adhesion
R. Molteni1, C.L. Crespo1, M. Fabbri1, S. Feigelson2, R. Alon2, G. Innamorati3, F. Krombach4, R. Pardi1
1Leukocyte Biology Unit, DIBIT, San Raffaele Scientific Inst. and Univ. Vita-Salute San Raffaele (Milan); 2Dept of Immunology, Weizmann Institute of Science (Rehovot , Israel); 3Univ. di Verona (Verona); 4Institute for Surgical Research, Univ. of Munich (Munich, Germany)

β-Arrestins as signaling intermediates in chemokine-induced leukocyte adhesion
R. Molteni1, C.L. Crespo1, M. Fabbri1, S. Feigelson2, R. Alon2, G. Innamorati3, F. Krombach4, R. Pardi1
1Leukocyte Biology Unit, DIBIT, San Raffaele Scientific Inst. and Univ. Vita-Salute San Raffaele (Milan); 2Dept of Immunology, Weizmann Institute of Science (Rehovot , Israel); 3Univ. di Verona (Verona); 4Institute for Surgical Research, Univ. of Munich (Munich, Germany)
PMS.12 · P27 
ADAM10 mediates RAGE shedding: a possible role in acute lung injury
A. Raucci1, A. Antonelli1, J. Rejman2, M.E. Bianchi3
1Chromatin Dynamics Unit, San Raffaele Scientific Inst. (Milan); 2Institute for experimental treatment of cystic fibrosis, San Raffaele Scientific Inst. (Milan); 3Chromatin Dynamics Unit, Vita-Salute San Raffaele Univ. (Milan)

ADAM10 mediates RAGE shedding: a possible role in acute lung injury
A. Raucci1, A. Antonelli1, J. Rejman2, M.E. Bianchi3
1Chromatin Dynamics Unit, San Raffaele Scientific Inst. (Milan); 2Institute for experimental treatment of cystic fibrosis, San Raffaele Scientific Inst. (Milan); 3Chromatin Dynamics Unit, Vita-Salute San Raffaele Univ. (Milan)
PMS.12 · P28 
The regulated exocytosis of enlargeosomes: identification of SNAREs that participate in the machinery
G. Racchetti1, E. Cocucci2, M. Rupnik3, J. Meldolesi1,2
1Fondazione Centro San Raffaele del Monte Tabor (Milan); 2Univ. Vita-Salute San Raffaele (Milan); 3Univ. di Maribor (Maribor, Slovenia)

The regulated exocytosis of enlargeosomes: identification of SNAREs that participate in the machinery
G. Racchetti1, E. Cocucci2, M. Rupnik3, J. Meldolesi1,2
1Fondazione Centro San Raffaele del Monte Tabor (Milan); 2Univ. Vita-Salute San Raffaele (Milan); 3Univ. di Maribor (Maribor, Slovenia)
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