PMS 1 · Transcriptional and post-transcriptional regulation
Thursday .::. 27 September .::. 14:00-16:00

PMS.1 · 0+P1    

Myosin VI is recruited to the nucleus upon transcriptional activation and modulates the elongation step
C. Ferrai, P. Luraghi, D. de Munari , S. Vreugde, M.P. Crippa
Laboratory of Moleuclar Genetics, DiBiT, S. Raffaele Scientific Inst. (Milan)

PMS.1 · 0+P2    

New snRNA gene-like transcriptional units as sources of regulatory transcripts
M. Castelnuovo¹, F. Tortelli¹, I. Vassallo¹, G. Fiorino², G. Dieci², R. Cancedda^1,3, A. Pagano^1,3
1Dip. Oncologia Biologia e Genetica, Univ. Genoa (Genoa); ²Dip. Biochimica e Biologia Molecolare, Univ. Parma (Parma); ³Istituto Nazionale per la Ricerca sul Cancro (Genoa)

PMS.1 · 0+P3    

A link between post-transcriptional gene silencing and DNA replication
G. Cecere¹, T. Nolan¹, G. Chiofalo¹, C. Mancone³, T. Alonzi³, C. Catalanotto^1,2, M. Tripodi^1,3, C. Cogoni^1,2
1Dept Cellular Biotechnology and hematology (BCE), Univ. La Sapienza (Rome); ²European Brain Reaseach Institute, Fondazione Rita Levi-Montalcini (Rome); ³National Institute for Infectious Diseases L. Spallanzani, IRCCS (Rome)

PMS.1 · 0+P4    

The RNase III Drosha controls miRNA biogenesis during transcription
F. Pagano, E. Girardi, D. de Cacchiarelli, M. Ballarino, I. Bozzoni
Dip. Genetica e Biologia Molecolare "Charles Darwin", Univ. Roma "La Sapienza" (Rome)

PMS.1 · 0+P5    

Mir-9, mir-125a and mir-125b are involved in the control of human neuroblastoma cell proliferation
U. Gioia¹, P. Laneve^1,2, L. Di Marcotullio³, M. Fiori¹, E. Ferretti³, A. Gulino³, I. Bozzoni^1,2, E. Caffarelli^2
1Dept Genetics and Molecular Biology, "La Sapienza", Univ. Rome (Rome); ²Institute of Molecular Biology and Pathology, CNR (Rome); ³Dept Experimental Medicine, "La Sapienza", Univ. Rome (Rome)

PMS.1 · 0+P6    

ISWI Functionally Interacts with the SIN3A/RPD3 Complex
G. Burgio¹, G.L. Rocca¹, A. Sala¹, M. Collesano¹, J.W. Tamkun², D. de F.V. Corona^1
1Istituto Telethon Dulbecco, Univ. di Palermo, Dip. Scienze Biochimiche (Palermo); ²Dept of Molecular, Cell and Developmental Biology, Univ. of California (Santa Cruz, CA, USA)

PMS.1 · 0+P7    

Molecular characterization of CDKL5, a novel kinase involved in Rett Syndrome and Infantile Spasms
L. Rusconi, I. Bertani, B. Conca, A. Bergo, G. Forlani, L. Giudici, C. Kilstrup-Nielsen, N. Landsberger
Dept of Functional and Structural Biology (Busto Arsizio)

PMS.1 · 0+P8    

How to make a skin-tight dress: the p63/claudin-1 connection
N. Lo Iacono¹, T. Lopardo¹, F. Galli¹, D. Cyr², A. Costanzo³, L. Guerrini^1
1Dip. Scienze Biomolecolari e Biotecnologie, Univ. Milano (Milano); ²INRS- Université du Québec (QC, Canada); ³Dip. Dermatologia, Univ. Roma "Tor Vergata" (Rome)

PMS.1 · P9    

The 3'UTR of PKD1 messenger RNA confers miRNA-dependent post-transcriptional regulation of protein expression
R. Mueller¹, M. Albersmeyer², J. Heiss², B. Schermer¹, G. Walz², T. Benzing^1
1Renal Division, Univ. Hospital Cologne, Germany (Koeln, Germany); ²Renal Division, Univ. Hospital Freiburg (Freiburg, Germany)

PMS.1 · P10    

Effects of different air CO₂ concentration on NtAQP1 and NtPIP2 gene expression
F. Secchi, G. Viretto, C. Lovisolo, A. Schubert
Dept Arboriculture and Pomology, Univ. Turin (Grugliasco)

PMS.1 · P11    

RhoU, a Wnt-1 inducible Cdc42-like Rho GTPase, is a STAT3 transcriptional target
D. Schiavone, S. Dewilde, F. Vallania, V. Poli
Molecular Biotechnology Center, Dept Genetics Biology and Biochemistry, Univ. Turin (Turin)

PMS.1 · P12    

The response of the yeast Saccharomyces cerevisiae to caesium chloride
V. Casagrande, V.D. Vescovo, E. Piccinni, C. Militti, L. Frontali, R. Negri, M.M. Bianchi
Dept of Cell and Developmental Biology, Univ. of Rome "La Sapienza" (Rome)

PMS.1 · P13    

Poised transcription factories prime silent uPA genes prior to activation
C. Ferrai¹, S.Q. Xie², P. Luraghi¹, D. de Munari¹, A. Pombo², M.P. Crippa^1
1Laboratory of Molecular Genetics, DIBIT, S. Raffaele Scientific Inst. (Milan); ²MRC Clinical Sciences Centre, Imperial College School of Medicine, Hammersmith Hospital Campus, Du Cane Road (London , United Kingdom)

PMS.1 · P14    

Phosphorylation of CRYPTOCHROME (dCRY), a circadian photoreceptor in Drosophila melanogaster
M. Mason¹, M.A. Pagano^2,3, G. Mazzotta¹, F. Sandrelli¹, S. Ferrari⁴, F. Meggio^2,3, R. Costa^1
1Dept Biology, Univ. Padua (Padua); ²Dept of Biological Chemistry, Univ. Padua (Padua); ³CNR, Univ. Padua (Padua); ⁴Institute of Molecular Cancer Research, Univ. Zurich (Zurich, Switzerland)

PMS.1 · P15    

The role of E2F factors in the control of the expression of dhfr/ts genes of Arabidopsis thaliana
S. Ghisaura¹, R. Giordo¹, R. Sozzani², R. Cella², D. Albani^1
1Dept of Botany and Plant Ecology, Univ. Sassari (Sassari); ²Dept of Genetics and Microbiology, Univ. of Pavia (Pavia)

PMS.1 · P16    

The yeast RasGEF Cdc25 is involved both in Ras-dependent and Ras-independent transcriptional regulation
R. Tisi, B. Vrancx, E. Martegani
Dept Biotechnology and Biosciences, Univ. Milano-Bicocca (Milan)

PMS.1 · P17    

Identification and characterizationof gene involved in Stellate repression
M.C. Onorati, B. Perrini, L. Piacentini, L. Fanti, S. Pimpinelli
Dep. of Genetics and Molecular Biology, Sapienza Univ. of Rome (Rome)

PMS.1 · P18    

Prediction and experimental validation of natural antisense transcripts in two cancer-associated regions of human chr. 6
L. Monti¹, R. Cinquetti¹, A. Guffanti², M. Cremona³, G. Lavorgna⁴, D. Cittaro⁵, P. Campomenosi¹, R. Taramelli¹, F. Acquati^1
1Dept of Biotechnologies and Molecular Sciences, Univ. Insubria (Varese); ²Nanotechnologies Group, ­ Institute of Biomedical Technologies, CNR (Milan); ³Proteomic Unit, Dept of Experimental Oncology, Istituto Nazionale Tumori (Milan)

PMS.1 · P19    

The RNA-binding protein PLAUF: promoter characterisation and functional assays
D.S. Matassa¹, R. Fusco¹, M. Napolitano¹, M. Piscopo¹, M. Branno², L. Fucci^1
1Dept Structural and Functional Biology, Univ. Napoli (Naples); ²Stazione Zoologica A. Dohrn (Naples)

PMS.1 · P20    

SUMO controls the protein stability of the transcription factor Pax8
T. de Cristofaro¹, A. Pappalardo², A. Mascia¹, S. Zannini^1
1Istituto per l'Endocrinologia ed Oncologia Sperimentale (IEOS), CNR (Napoli); ²Dip. di Biologia e Patologia Cellulare e Molecolare, Univ. Federico II (Napoli)

PMS.1 · P21    

aubergine and dfmr1, the Drosophila homolog of the human fragile X mental retardation gene, interact in the RNAi pathway
V. Specchia¹, A. Geusa¹, B. Sahin⁴, G. Palumbo³, S. Pimpinelli², A. Giangrande⁴, M.P. Bozzetti^1
1Dept Biological Enviromental Science (DiSTeBA) (Lecce); ²Dip. Genetica e Biologia molecolare Univ. La Sapienza (Roma); ³Dip. Genetica e Microbiologia Univ. Bari (Bari); ⁴IGBMC (Illkirch, France)

PMS.1 · P22    

Analysis of in-cis elements and trans factors promoting pseudoexon inclusion in the fibrinogen γ-chain (FGG) transcript
S. Spena¹, R. Asselta¹, E. Buratti², G. Castaman³, M.L. Tenchini¹, S. Duga^1
1Dept of Biology and Genetics for Medical Sciences, Univ. of Milan (Milan); ²International Centre for Genetic Engineering and Biotechnology, ICGEB (Trieste); ³Dept of Hematology and Hemophilia and Thrombosis Center, San Bortolo Hospital (Vicenza)

PMS.1 · P23    

Role of Δ5Tfam in mitochondrial transcription
S. Bruno, C. de Virgilio, G. Gadaleta
Dip. Biochimica e Biologia Molecolare (Bari)

PMS.1 · P24    

Tha katG mRNA of M. tuberculosis is processed and stabilized by both a polypurine sequence and translation initiation
F. Magnoni, C. Sala, F. Forti, D. Ghisotti
Dept Biomolecular Sciences and Biotechnology, Univ. Milan (Milan)

PMS.1 · P25    

Expression of TTDN1 in different cell types from patients affected by trichothiodystrophy
M. Lanzafame¹, T. Nardo¹, D. Orioli¹, M. Teson², G. Zambruno², M. Stefanini¹, E. Botta^1
1Istituto di Genetica Molecolare, CNR (Pavia); ²Istituto Dermopatico dell'Immacolata, IRCCS (Rome)

PMS.1 · P26    

The 3'UTR of human CDK5R1 contains regulatory elements affecting transcript stability and binds nELAV
S. Moncini¹, A. Bevilacqua², M. Venturin¹, C. Fallini³, A. Ratti³, A. Nicolin², P. Riva^1
1Dept Biology and Genetics for Medical Sciences, Univ. Milan (Milan); ²Dept of Pharmacology, Chemotherapy and Medical Toxicology, Univ. Milan (Milan); ³Dept of Neuroscience, Univ. Milan, IRCCS Istituto Auxologico Italiano (Milan)

PMS.1 · P27    

Arabidopsis thaliana MBD7 protein interacts with the arginine methyltransferase AtPRMT11
M. de Bastiani¹, F. Scebba², A. Andreucci³, A. Galli², L. Pitto², G. Bernacchia^1
1Dept Biology and Evolution, Univ. Ferrara (Ferrara); ²Clinical Physiology Institute, CNR (Pisa); ³Dept Botanical Sciences, Univ. Pisa (Pisa)

PMS.1 · P28    

PARP-1 regulates Pax8 transcriptional activity
T. Di Palma¹, T. de Cristofaro², D.D. Prete², S. Zannini^2
1IEOS-CNR and DBPCM, Univ. Naples Federico II (Naples); ²IEOS-CNR (Naples)

PMS.1 · P29    

Maintenance of skeletal muscle: role of mRNA post-transcriptional regulation
B. Cardinali¹, S. Galletti¹, L. Castellani¹, S. Alemà¹, P. Fasanaro², F. Martelli², G. Falcone^1
1Istituto di Biologia Cellulare, CNR (Monterotondo Scalo, Roma); ²Istituto Dermopatico Immacolata, IDI-IRCCS (Roma)

PMS.1 · P30    

The non-coding RNA contribution to Alzheimer Disease
I. Vassallo¹, M. Castelnuovo¹, C. Russo⁴, G. Fiorino³, R. Borghi², R. Cancedda¹, G. Dieci³, A. Pagano^1
1Dept Oncology Biology and Genetics, Univ. Genoa (Genoa); ²Dip. Neurologia, Univ. Genova (Genoa); ³Dip. Biochimica e Biologia Molecolare, Univ. Parma (Parma); ⁴Dip. Scienze della Salute, Univ. del Molise (Campobasso)

PMS.1 · P31    

Promoter hypomethylation, Egr1 and Sp1 regulate p57KIP2 expression during muscle differentiation
A. Busanello, R. Figliola, G. Vaccarello, R. Maione
Dip. Biotecnologie Cellulari ed Ematologia, Sezione di Genetica Molecolare, Univ. Roma La Sapienza (Rome)

PMS.1 · P32    

Genome-wide discovery of functional STAT3 binding sites
F. Vallania¹, M. Pontoglio², S. Garbay², P. Provero¹, V. Poli^1
1Molecular Biotechnology Center, Univ. Turin (Turin); ²Dép. de Biologie du Développement, Institut Pasteur (Paris, France)

PMS.1 · P33    

Overexpression of Matrix Metalloproteinase-I (MMP-1) in primary skin fibroblasts from patients with trichothiodystrophy
D. Orioli, A. Barroso, T. Nardo, F. Peverali, M. Stefanini
Istituto Genetica Molecolare CNR Pavia (Pavia)

PMS.1 · P34    

TTF-1/NKX2.1 regulates the transcription of the neuroepithelial marker nestin in vivo
R. Pelizzoli, C. Tacchetti, P. Luzzi, A. Strangio, S. Guazzi
Dept Experimental Medicine, Univ. Genova and IFOM Center of Cell Oncology and Ultrastructure (Genoa)

PMS.1 · P35    

Regulation of the expression of two genes involved in mtDNA transcription in Drosophila: role of the nuclear factor DREF
F. Bruni¹, M.A.F. Moreno², C. Manzari¹, P.L. Polosa¹, M.N. Gadaleta¹, P. Cantatore¹, R. Garesse², M. Roberti^1
1Dip. Biochimica e Biologia Molecolare Univ. Bari (Bari); ²Dept de Bioquimica, Istituto de Investigaciones Biomedicas "Alberto Sols" CSIC-UAM Univ. Autonoma de Madrid (Madrid, Spain)

PMS.1 · P36    

Differential expression of microRNAs between eutopic and ectopic endometrium in endometriosis
N. Filigheddu¹, P.E. Porporato², I. Gregnanin¹, A. Romano¹, A. Graziani², N. Surico^1
1Dept Clinical and Experimental Medicine, Univ Piemonte Orientale (Novara); ²Dept Medical Sciences (Novara)

PMS.1 · P37    

Transcriptional analysis of ESAT-6 cluster 3 in Mycobacterium tuberculosis and Mycobacterium smegmatis
A. Maciag, A. Milano
Dip. Genetica e Microbiologia, Univ. Pavia (Pavia)

PMS.1 · P38    

A role for PRMT5 in the regulation of Aldolase A gene expression
E. Cesaro¹, L. Medugno¹, F. Florio¹, A. Lupo², S. Salzano³, M. Grosso¹, P. Izzo¹, P. Costanzo^1
1Dip. Biochimica e Biotecnologie Mediche, Univ. Napoli "Federico II" (Naples); ²Dip. Scienze Biologiche ed Ambientali, Facoltà di Scienze MM.FF.NN., Unisannio (Benevento); ³Istituto di Endocrinologia ed Oncologia Sperimentale G. Salvatore, CNR (Naples)

PMS.1 · P39    

Insights into the general transcription factor TFIIE
H. Pinto, D. Orioli, T. Nardo, R. Guglielmino, F.A. Peverali, M. Stefanini
Istituto di Genetica Molecolare CNR (Pavia)

PMS.1 · P40    

Proteasome-regulated expression of the transcription factor REST during neuronal differentiation
R. Di Toro, M. Baiula, S. Spampinato
Dept of Pharmacology, Univ. of Bologna (Bologna)

PMS.1 · P41    

Human aldolase C messenger expression during brain development in transgenic mice
A. Mancini², L. Serio¹, A. Alfieri³, O. Barbieri⁴, S. Astigiano⁴, P. Buono^2,3, F. Salvatore^1,2
1CEINGE Biotecnologie Avanzate s.ca.r.l. (Napoli); ²DBBM, Univ.Federico II (Napoli); ³Fondazione SDN -IRCCS e DISiST-Univ. Parthenope (Napoli); ⁴Dip. di Oncologia, Biologia e Genetica, Univ. Genova ;Ist.Naz.Ricerca sul cancro (Genova)

PMS.1 · P42    

The DAG1 transcription factor from Arabidopsis thaliana: study of its transcriptional/post-transcriptional regulation
P. Circelli¹, J. Martone¹, A. Rizza¹, S. Gabriele¹, G. Ragone², P. Costantino¹, P. Vittorioso^1
1Dept Genetics and Molecular Biology, Univ. Rome (Rome); ²Istituto Dermopatico dell'Immacolata (Rome)

PMS.1 · P43    

Identification of direct Hox target genes in the Drosophila heart
M.F. Tevy¹, B. Zeitouni², F. Buontempo¹, E. Tosi¹, S. Aerts³, L. Perrin², M. Sémériva², M. Capovilla^1
1Dulbecco Telethon Inst., Dept of Biology and Evolution, Univ. Ferrara (Ferrara); ²IBDML, CNRS (Marseille, France); ³Laboratory of Neurogenetics, Dept of Molecular and Developmental Genetics, Univ. Leuven (Leuven, Belgium)

PMS.1 · P44    

The SnRK1 gene of Zea mays: strucrure and tissue specific regulatory mechanisms
F. Gavazzi¹, A. Genga¹, C. Cosentino¹, L. Concia¹, B. Lazzari², R.J. Schmidt³, A. Viotti^1
1Ist. Biologia Biotecnologia Agraria, CNR (Milan); ²Parco Tecnologico Padano (Lodi); ³Dept Biology, UCSD (San Diego, California, USA)

PMS.1 · P45    

Interaction between the inner nuclear membrane lamin B receptor and the heterocromatic methyl binding protein MeCP2
A. Guarda, F. Bolognese, G. Badaracco
Dip. Biologia Strutturale e Funzionale, Univ. dell' Insubria (Busto Arsizio)

PMS.1 · P46    

Short sequence motifs enriched in promoters of human genes transcriptionally regulated by statins in FCHL patients
V. de Simone^1,2, I. Donnarumma¹, L. Gambardella¹, M. Romano¹, L. de Magistris¹, R. Martinelli^1,2
1Dept of Biochemistry and Medical Biotechnology, Univ. of Naples "Federico II" (Naples); ²CEINGE Biotecnologie Avanzate (Naples)

PMS.1 · P47    

Identification of new microRNAs potentially involved in muscle differentiation
E. Turri¹, S. Vincenti¹, M. Pompili², A. Alteri², M. Grossi², C. Presutti^1
1Dept of Genetic and Mol. Biology, Univ. "La Sapienza" (Rome); ²Dept of Cellular and Developmental Biology, Univ. La Sapienza (Rome)

PMS.1 · P48    

Sub-cellular localization of mRNAs encoding cytosolic and mitochondrial ribosomal proteins
G. Russo¹, A. Russo¹, G. Siciliano¹, C. Garbi², C. Pietropaolo^1
1Dept Biochemical and Medical Biotechnologies, Univ. Napoli (Napoli); ²Dip. di Biologia e Patologia Cellulare e Molecolare, University Federico II (Naples)

PMS.1 · P49    

The EBV Latent Membrane Protein 1 enhances miR-155 transcription through NF-kB pathway
G. Gatto, A. Rossi, S. Kroening, A. D'Ambrosio, S. Bonatti, M. Mallardo
Dip. Biochimica e Biotecnologie Mediche, Univ. di Napoli Federico II (Naples)

PMS.1 · P50    

Interaction of the Wilms Tumor Suppressor Gene, WT1, with ZNF224 and ZNF255
F. Florio¹, L. Spraggon², L. Medugno¹, E. Cesaro¹, P. Izzo¹, C. Miles², P. Costanzo^1
1Dip. Biochimica e Biotecnologie Mediche, Univ. Napoli "Federico II" (Naples); ²Institute of Human Genetics, International Centre for Life, Newcastle upon Tyne (Newcastle, United Kingdom)

PMS.1 · P51    

Phosphomimetic mutations of the p63 transcription factor are associated to the SHFM-IV and EEC human syndromes
F. Galli, T. Lopardo, N. Lo Iacono, L. Guerrini
Dip. scienze biomolecolari e biotecnologie, Univ. Milano (Milan)

PMS.1 · P52    

Regulation of ribosome synthesis and function
F. Loreni, S. Caldarola, V. Iadevaia, M.C. de Stefano, L. Biondini, F. Amaldi
Dept Biology, Univ. of Rome "Tor Vergata" (Rome)

PMS.1 · P53    

Identification and functional characterization of novel mammal-specific LSD1 splicing isoforms
A. Adamo¹, C. Zibetti¹, A. Dall'aglio¹, A. Borali¹, A. Mattevi², E. Ginelli¹, E. Battaglioli^1
1Dept of Biology and Genetics for Medical Science, Univ. Milan (Milan); ²Dept of Genetics and Microbiology, Univ. of Pavia (Pavia)

PMS.1 · P54    

Cross-regulation of PHOX2A and PHOX2B transcription factors in the development of the Autonomic Nervous System
S. Di Lascio^1,2,3, F. Cargnin^1,2,3, F. Clementi^1,2,3, D. Fornasari^1,2,3, R. Benfante^1,2,3
1Dept of Pharmacology, School of medicine, Univ. Milan (Milan); ²CNR, Inst. of Neuroscience, Cellular and Molecular Pharmacology Division (Milan); ³CEND, Center of Excellence on Neurodegenerative Diseases, Univ. of Milan (Milan)

PMS.1 · P55    

Retinoic acid controls PHOX2A expression by means of a dual regulatory mechanism
R. Benfante^1,2,3, H. Lucchetti^1,2,3, E. Saba^1,2,3, F. Clementi^1,2,3, D. Fornasari^1,2,3
1Dept Of Pharmacology, School of Medicine, Univ. Milan (Milan); ²CNR, Institute of Neuroscience, Cellular and Molecular Pharmacology Division (Milan); ³CEND, Center of Excellence on Neurodegenerative Diseases, Univ. of Milan (Milan)

PMS.1 · P56    

Analysis of the hinT gene promoter of Escherichia coli
L. D'Imperio, A. Frandi, M. Brilli, M. Fondi, M. Bazzicalupo, E.G. Biondi, A. Mengoni, R. Fani
Dept of Animal Biology and Genetics, Univ. Florence (Florence)

PMS.1 · P57    

Micro-RNA expression aleration under stress condition in the mouse brain
P. Fragapane¹, A. Rinaldi^2,3,4, S. Vincenti², A. Oliverio^2,3,4, I. Bozzoni², A. Mele^2,3,4, C. Presutti^2
1Istituto di Biologia e Patologia molecolari CNR Roma (Rome); ²Dip. Genetica e Biologia molecolare Univ. "La Sapienza" (Rome); ³Ist. Neuroscienze CNR-CERC (Rome); ⁴Centro Ricerche in Neurobiologia "D.Bovet" (Rome)